LIS Technologies

LIS Technologies (LIST) is a nuclear energy technology company developing a patented laser isotope separation technology for uranium enrichment. The company’s proprietary process, called Condensation Repression Isotope Selective Laser Activation (CRISLA), uses infrared lasers to selectively excite molecules of desired uranium isotopes (UF6) to separate them from other isotopes. This third-generation enrichment technology offers superior efficiency and cost-effectiveness compared to first-generation diffusion plants and second-generation centrifuge plants, with a separation factor exceeding 3, often described as the holy grail of enrichment. LIST’s technology produces Low Enriched Uranium (LEU) for use in large civil reactors and High-Assay Low-Enriched Uranium (HALEU) for next-generation Small Modular Reactors (SMRs) and microreactors. The technology is USA-origin and patented, addressing the gap in global commercial uranium enrichment capacity currently dominated by Russia, Europe, and China. The company benefits from U.S. executive orders channeling billions of dollars into rebuilding the domestic nuclear fuel ecosystem, supporting energy independence and AI-driven power demand from hyperscalers. Founded in 2023 and headquartered in New York City, the company has raised approximately $71.6 million in Series A funding. Investors include 28 Ventures, Nano Nuclear, Innovating Capital, and Minetta Brook Capital.