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Life Sciences Seed Founded 2017

Shift Bioscience

Shift Bioscience is a biotechnology company developing cell rejuvenation therapies to reverse age-driven diseases by targeting the aging cell. The company has built a best-in-class target discovery platform combining a novel aging clock (AC4) and virtual cell model to remove the primary bottleneck for discovery of cellular aging and rejuvenation targets, enabling identification of hundreds of novel targets linked to…

📍 Cambridge, United Kingdom · Gene Therapy,

Funding snapshot

Last roundSeed
Amount$16M
Date16 October 2024
Total raised$29M
Team size24

About

Shift Bioscience is a biotechnology company developing cell rejuvenation therapies to reverse age-driven diseases by targeting the aging cell. The company has built a best-in-class target discovery platform combining a novel aging clock (AC4) and virtual cell model to remove the primary bottleneck for discovery of cellular aging and rejuvenation targets, enabling identification of hundreds of novel targets linked to disease states. Its lead product, SB101, is an anti-fibrotic siRNA therapeutic that reverses epigenetic aging clocks in multiple cell types through a genetically validated fibrosis pathway, with first-in-class opportunities in liver fibrosis and expansion potential to secondary fibrosis in lung and heart. The company has published research on AI virtual cells for genetic perturbation modeling and holds a comprehensive IP package with patent life extending to 2046. Founded in 2017 and headquartered in Cambridge, UK, with computational operations in Toronto, Canada, Shift Bioscience has raised approximately $28.6M in seed funding from investors including BGF, F-Prime Capital, Kindred Capital, and Healthspan Capital.

Business model

Gastroenterology > Drugs > Liver Diseases,

ENT Disorders > Drugs,

Genomics > Applied Genomics > Clinical Genomics > Therapeutics > Cellular Rejuvenation

Team background

College Wise > University of Cambridge

Institutional investors

BGF F-Prime Capital Kindred Capital Boost VC Healthspan Capital IKJ Capital Thelettingscentre galloway DG Global Ventures Jonathan Milner Roza Gounari Stephen Ives Johnnie Sam Karl Pfleger Miron Cuperman

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