Siren

Siren is a digital health company that develops smart socks for preventing diabetic foot ulcers through continuous temperature monitoring. The socks are embedded with sensors that track foot temperature, an early indicator of inflammation and potential injury that may lead to ulcers, which affect over 30 percent of people with diabetes during their lifetime. When temperature increases are detected, licensed nurses review the data and contact patients regularly, while providers are alerted to potential injuries for clinical follow-up. Clinical research has shown that temperature monitoring can reduce diabetic foot ulcers by up to 87.5 percent. Siren socks require no smartphone, are machine washable, do not need charging, and are automatically replaced when worn down. The company serves patients, healthcare providers, and payers, with certified Siren providers distributing the product through podiatry clinics. Founded in 2015 and headquartered in San Francisco, Siren has raised $43 million through Series B funding from investors including Khosla Ventures, DCM Ventures, Founders Fund, and Mighty Capital.