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Life Sciences Series B Founded 2012

Xcell Biosciences

Xcell Biosciences develops the AVATAR platform, a cell therapy manufacturing technology that brings physiologically relevant tumor microenvironment (TME) control into cell therapy workflows. The platform integrates physiologic oxygen and pressure control directly into GMP workflows to train cells for the environments they face in vivo, improving potency, persistence, and predictability for solid tumor therapies. Its…

📍 San Francisco, United States · Genomics,

Funding snapshot

Last roundSeries B
Amount$1M
Date6 December 2024
Total raised$41M
Team size17

About

Xcell Biosciences develops the AVATAR platform, a cell therapy manufacturing technology that brings physiologically relevant tumor microenvironment (TME) control into cell therapy workflows. The platform integrates physiologic oxygen and pressure control directly into GMP workflows to train cells for the environments they face in vivo, improving potency, persistence, and predictability for solid tumor therapies. Its product line includes ODYSSEY for R&D and process development optimization, FOUNDRY for clinical and commercial manufacturing with closed, automated scale-up, and AI for functional evaluation using machine-learning models for rapid potency assessment. AVATAR-expanded CAR T cells demonstrate 70% greater potency under TME conditions compared to conventional methods, selectively expanding Tcm and Tscm populations associated with efficacy. Founded in 2012 and headquartered in San Francisco, California, Xcell Biosciences has raised approximately $40.9M in Series B funding from investors including Illumina, Casdin Capital, DST Global, Lightspeed Venture Partners, Viking Global Investors, and LabCorp.

Business model

Oncology > In-Vitro Diagnostic Tests > Diversified > Precision Medicine,

Genomics > Enabling Technologies > Instrument Systems > Single Cell Genomics,

Life Sciences Platforms and Tools > Instruments > Cell Biology > Cell Analysis

Team background

College Wise > University of California (Berkeley)

Institutional investors

HBM Genomics Illumina Casdin Capital Dynamk Capital Formic Ventures LabCorp Viking Global Investors Lightspeed Venture Partners Berkeley SkyDeck PavLyfe DST Global Avego

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